Prof. Dr. Evelyn Lamy

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2004

2024

Pfäffle Simon P., Herz Corinna, Brombacher Eva, Proietti Michele, Gigl Michael, Hofstetter Christoph K., Mittermeier-Kleßinger Verena K., Claßen Sophie, Tran Hoai T. T., Dawid Corinna, Kreutz Clemens, Günther Stefan, Lamy Evelyn. A 14-day double-blind, randomized, controlled crossover intervention study with anti-bacterial benzyl isothiocyanate from nasturtium (Tropaeolum majus) on human gut microbiome and host defense. https://doi.org/10.3390/nu16030373
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2023

Herz Corinna, Frei Linda, Tran Hoai T. T., Claßen Sophie, Spöttel Jenny, Krell Mareike, Hanschen Franziska S., Arvandi Marjan, Binder Nadine, Schreiner Monika, Rohn Sascha, Lamy Evelyn. A monocentric, randomized, double-blind, controlled crossover trial of nasturtium (tropaeolum majus) on the lipid regulator prostaglandin E2. https://doi.org/10.3389/fnut.2023.1223158
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Moumbock Aurélien F. A., Tran Hoai T. T., Lamy Evelyn, Günther Stefan. BC‐11 is a covalent TMPRSS2 fragment inhibitor that impedes SARS‐CoV‐2 host cell entry. https://doi.org/10.1002/ardp.202200371
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Le Nguyen Phan Khoi, Altenburger Markus Jörg, Lamy Evelyn. Development of an inflammation-triggered in vitro "leaky gut" model using Caco-2/HT29-MTX-E12 combined with macrophage-like THP-1 cells or primary human-derived macrophages. https://doi.org/10.3390/ijms24087427
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2022

Thi Thu Tran Hoai, Lamy Evelyn. Bisphenol A and its impact on human telomerase, telomere length and cell aging. https://doi.org/10.1039/9781839166495-00087
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Tran Hoai Thi Thu, Gigl Michael, Dawid Corinna, Lamy Evelyn. Common dandelion (Taraxacum officinale) leaf extract efficiently inhibits SARS-CoV-2 Omicron infection in vitro. https://doi.org/10.1101/2022.12.22.521558
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Tran Hoai Thi Thu, Peterburs Philipp, Seibel Jan, Abramov-Sommariva D., Lamy Evelyn. In vitro screening of herbal medicinal products for their supportive curing potential in the context of SARS-CoV-2. https://doi.org/10.1155/2022/8038195
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2021

Tran Hoai T. T., Stetter Rebecca, Herz Corinna, Spöttel Jenny, Krell Mareike, Hanschen Franziska S., Schreiner Monika, Rohn Sascha, Behrens Maik, Lamy Evelyn. Allyl isothiocyanate: a TAS2R38 receptor-dependent immune modulator at the interface between personalized medicine and nutrition. https://doi.org/10.3389/fimmu.2021.669005
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Festa Ortega Juliana, Heidor Renato, Auriemo Ana Paula, Marques Affonso Juliana, Pereira D'Amico Thais, Herz Corinna, de Conti Aline, Ract Juliana, Gioieli Luiz Antônio, Purgatto Eduardo, Lamy Evelyn, Pogribny Igor P., Salvador Moreno Fernando. Butyrate-containing structured lipids act on HDAC4, HDAC6, DNA damage and telomerase activity during promotion of experimental hepatocarcinogenesis. https://doi.org/10.1093/carcin/bgab039
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Le Nguyen, Herz Corinna, Gomes João, Förster Nadja, Antoniadou Kyriaki, Mittermeier-Kleßinger Verena, Mewis Inga, Dawid Corinna, Ulrichs Christian, Lamy Evelyn. Comparative anti-inflammatory effects of salix cortex extracts and acetylsalicylic acid in SARS-CoV-2 peptide and LPS-activated human in vitro systems. https://doi.org/10.3390/ijms22136766
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Dutra Gomes João Victor, Herz Corinna, Helmig Simone, Förster Nadja, Mewis Inga, Lamy Evelyn. Drug-drug interaction potential, cytotoxicity, and reactive oxygen species production of Salix cortex extracts using human hepatocyte-like HepaRG cells. https://doi.org/10.3389/fphar.2021.779801
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Antoniadou Kyriaki, Herz Corinna, Le Nguyen Phan Khoi, Mittermeier-Kleßinger Verena Karolin, Förster Nadja, Zander Matthias, Ulrichs Christian, Mewis Inga, Hofmann Thomas, Dawid Corinna, Lamy Evelyn. Identification of salicylates in willow bark (Salix cortex) for targeting peripheral inflammation. https://doi.org/10.3390/ijms222011138
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Tran Hoai Thi Thu, Gigl Michael, Le Nguyen Phan Khoi, Dawid Corinna, Lamy Evelyn. In vitro effect of Taraxacum officinale leaf aqueous extract on the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614 and four mutants. https://doi.org/10.3390/ph14101055
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Wiesner-Reinhold Melanie, Dutra Gomes João Victor, Herz Corinna, Tran Hoai Thi Thu, Baldermann Susanne, Neugart Susanne, Filler Thomas, Glaab Johannes, Einfeldt Sven, Schreiner Monika, Lamy Evelyn. Subsequent treatment of leafy vegetables with low doses of UVB-radiation does not provoke cytotoxicity, genotoxicity, or oxidative stress in a human liver cell model. https://doi.org/10.1016/j.fbio.2021.101327
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Moumbock Aurélien F. A., Li Jianyu, Tran Hoai T. T., Hinkelmann Rahel, Lamy Evelyn, Jessen Henning J., Günther Stefan. ePharmaLib: a versatile library of e-pharmacophores to address small-molecule (poly-)pharmacology. https://doi.org/10.1021/acs.jcim.1c00135
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2020

Tran Hoai Thi Thu, Herz Corinna, Lamy Evelyn. Long-term exposure to "low-dose" bisphenol A decreases mitochondrial DNA copy number, and accelerates telomere shortening in human CD8 + T cells. https://doi.org/10.1038/s41598-020-72546-x
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Antoniadou Kyriaki, Herz Corinna, Lamy Evelyn, Förster Nadja, Mewis Inga, Ulrichs Christian, Zander Matthias, Mähler Nicole, Petersburg Philipp, Dawid Corinna. Targeted salix chemoprofiling for improved medicinal potential of willow bark. https://doi.org/10.1002/lemi.202051013
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2019

Odongo Grace A., Skatchkov Ivan, Herz Corinna, Lamy Evelyn. Optimization of the alkaline comet assay for easy repair capacity quantification of oxidative DNA damage in PBMC from human volunteers using aphidicolin block. https://doi.org/10.1016/j.dnarep.2019.03.005
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Tran Hoai, Schlotz Nina, Schreiner Monika, Lamy Evelyn. Short-term dietary intervention with cooked but not raw brassica leafy vegetables increases telomerase activity in CD8+ lymphocytes in a randomized human trial. https://doi.org/10.3390/nu11040786
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2018

Odongo Grace Akinyi, Schlotz Nina, Baldermann Susanne, Neugart Susanne, Huyskens-Keil Susanne, Ngwene Benard, Trierweiler Bernhard, Schreiner Monika, Lamy Evelyn. African nightshade (Solanum scabrum Mill.): impact of cultivation and plant processing on its health promoting potential as determined in a human liver cell model. https://doi.org/10.3390/nu10101532
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Schlotz Nina, Odongo Grace A., Herz Corinna, Waßmer Hanna, Kühn Carla, Hanschen Franziska S., Neugart Susanne, Binder Nadine, Ngwene Benard, Schreiner Monika, Rohn Sascha, Lamy Evelyn. Are raw brassica vegetables healthier than cooked ones? A randomized, controlled crossover intervention trial on the health-promoting potential of Ethiopian kale. https://doi.org/10.3390/nu10111622
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Kühn Carla, Kupke Franziska, Baldermann Susanne, Klopsch Rebecca, Lamy Evelyn, Hornemann Silke, Pfeiffer Andreas F. H., Schreiner Monika, Hanschen Franziska S., Rohn Sascha. Diverse excretion pathways of benzyl glucosinolate in humans after consumption of nasturtium (Tropaeolum majus L.) - a pilot study. https://doi.org/10.1002/mnfr.201800588
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Odongo Grace A., Schlotz Nina, Baldermann Susanne, Neugart Susanne, Ngwene Benard, Schreiner Monika, Lamy Evelyn. Effects of Amaranthus cruentus L. on aflatoxin B1- and oxidative stress-induced DNA damage in human liver (HepG2) cells. https://doi.org/10.1016/j.fbio.2018.09.006
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Tran Hoai T. T., Herz Corinna, Ruf Patrick, Stetter Rebecca, Lamy Evelyn. Human T2R38 bitter taste receptor expression in resting and activated lymphocytes. https://doi.org/10.3389/fimmu.2018.02949
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Kühn Carla, von Oesen Tobias, Herz Corinna, Schreiner Monika, Hanschen Franziska S., Lamy Evelyn, Rohn Sascha. In vitro determination of protein conjugates in human cells by LC-ESI-MS/MS after benzyl isothiocyanate exposure. https://doi.org/10.1021/acs.jafc.8b01309
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Fechner Jana, Kaufmann Martin, Herz Corinna, Eisenschmidt Daniela, Lamy Evelyn, Kroh Lothar W., Hanschen Franziska S.. The major glucosinolate hydrolysis product in rocket ( Eruca sativa L.), sativin, is 1,3-thiazepane-2-thione: elucidation of structure, bioactivity, and stability compared to other rocket isothiocyanates. https://doi.org/10.1016/j.foodchem.2018.04.023
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2017

Schloß Svenja, Hackl Thomas, Herz Corinna, Lamy Evelyn, Koch Matthias, Rohn Sascha, Maul Ronald. Detection of a toxic methylated derivative of phomopsin A produced by the legume-infesting fungus Diaporthe toxica. https://doi.org/10.1021/acs.jnatprod.6b00662
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Herz Corinna, Tran Hoai Thi Thu, Márton Melinda-Rita, Maul Ronald, Baldermann Susanne, Schreiner Monika, Lamy Evelyn. Evaluation of an aqueous extract from horseradish root (Armoracia rusticana radix) against lipopolysaccharide‐induced cellular inflammation reaction. https://doi.org/10.1155/2017/1950692
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Schlotz Nina, Kim Gwang-Jin, Jäger Stefan, Günther Stefan, Lamy Evelyn. In vitro observations and in silico predictions of xenoestrogen mixture effects in T47D-based receptor transactivation and proliferation assays. https://doi.org/10.1016/j.tiv.2017.08.017
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Herz Corinna, Tran Hoai Thi Thu, Schlotz Nina, Michels Karin, Lamy Evelyn. Low-dose levels of bisphenol A inhibit telomerase via ER/GPR30-ERK signalling, impair DNA integrity and reduce cell proliferation in primary PBMC. https://doi.org/10.1038/s41598-017-15978-2
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Herz Corinna, Tran Hoai Thi Thu, Landerer Steffen, Gaus Johanna, Schlotz Nina, Lehr Lia, Schäfer Wolfgang R., Treeck Oliver, Odongo Grace Akinyi, Skatchkov Ivan, Lamy Evelyn. Normal human immune cells are sensitive to telomerase inhibition by Brassica-derived 3,3-diindolylmethane,partly mediated via ERα/β-AP1 signaling. https://doi.org/10.1002/mnfr.201600524
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Odongo Grace Akinyi, Schlotz Nina, Herz Corinna, Hanschen Franziska S., Baldermann Susanne, Neugart Susanne, Trierweiler Bernhard, Frommherz Lara, Franz Charles M. A. P., Ngwene Benard, Luvonga Abraham Wahid, Schreiner Monika, Rohn Sascha, Lamy Evelyn. The role of plant processing for the cancer preventive potential of Ethiopian kale (Brassica carinata). https://doi.org/10.1080/16546628.2017.1271527
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2016

Herz Corinna, Márton Melinda-Rita, Tran Hoai Thi Thu, Gründemann Carsten, Schell Jana, Lamy Evelyn. Benzyl isothiocyanate but not benzyl nitrile from Brassicales plants dually blocks the COX and LOX pathway in primary human immune cells. https://doi.org/10.1016/j.jff.2016.02.034
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Kupke Franziska, Herz Corinna, Hanschen Franziska S., Platz Stefanie, Odongo Grace A., Helmig Simone, Bartolomé Rodríguez María M., Schreiner Monika, Rohn Sascha, Lamy Evelyn. Cytotoxic and genotoxic potential of food-borne nitriles in a liver in vitro model. https://doi.org/10.1038/srep37631
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Tran Hoai Thi Thu, Márton Melinda-Rita, Herz Corinna, Maul Ronald, Baldermann Susanne, Schreiner Monika, Lamy Evelyn. Nasturtium (Indian cress, Tropaeolum majus nanum) dually blocks the COX and LOX pathway in primary human immune cells. https://doi.org/10.1016/j.phymed.2016.02.025
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2015

Gründemann Carsten, Garcia-Käufer Manuel, Lamy Evelyn, Hanschen Franziska S., Huber Roman. 4-Methylthiobutyl isothiocyanate (Erucin) from rocket plant dichotomously affects the activity of human immunocompetent cells. https://doi.org/10.1016/j.phymed.2014.12.012
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Platz Stefanie, Piberger Ann Liza, Budnowski Julia, Herz Corinna, Schreiner Monika, Blaut Michael, Hartwig Andrea, Lamy Evelyn, Hanske Laura, Rohn Sascha. Bioavailability and biotransformation of sulforaphane and erucin metabolites in different biological matrices determined by LC–MS–MS. https://doi.org/10.1007/s00216-015-8482-z
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Hanschen Franziska S., Herz Corinna, Schlotz Nina, Kupke Franziska, Bartolomé Rodríguez María M., Schreiner Monika, Rohn Sascha, Lamy Evelyn. The Brassica epithionitrile 1‐cyano‐2,3‐epithiopropane triggers cell death in human liver cancer cells in vitro. https://doi.org/10.1002/mnfr.201500296
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2014

Hanschen Franziska S., Lamy Evelyn, Schreiner Monika, Rohn Sascha. Reactivity and stability of glucosinolates and their breakdown products in foods. https://doi.org/10.1002/anie.201402639
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Hanschen Franziska S., Lamy Evelyn, Schreiner Monika, Rohn Sascha. Reaktivität und Stabilität von Glucosinolaten und ihren Abbauprodukten in Lebensmitteln. https://doi.org/10.1002/ange.201402639
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Herz C., Hertrampf A., Stetter N., Schüler J., Mersch-Sundermann V., Lamy Evelyn. Relevance of telomerase inhibition by 4-methylthiobutyl isothiocyanate in tumor cells of the liver [Abstract]. https://doi.org/10.1055/s-0034-1394532
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Herz Corinna, Hertrampf Anke, Zimmermann Stefan, Stetter Nadine, Wagner Meike, Kleinhans Claudia, Erlacher Miriam, Schüler Julia, Platz Stefanie, Rohn Sascha, Mersch‐Sundermann Volker, Lamy Evelyn. The isothiocyanate erucin abrogates telomerase in hepatocellular carcinoma cells in vitro and in an orthotopic xenograft tumour model of HCC. https://doi.org/10.1111/jcmm.12412
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2013

Márton Melinda-Rita, Krumbein Angelika, Platz Stefanie, Schreiner Monika, Rohn Sascha, Rehmers Andreas, Lavric Vasile, Mersch-Sundermann Volker, Lamy Evelyn. Determination of bioactive, free isothiocyanates from a glucosinolate-containing phytotherapeutic agent: a pilot study with in vitro models and human intervention. https://doi.org/10.1016/j.fitote.2012.12.016
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Guo Jianing M., Klingner Kerstin, Krumbach Rebekka, Maier Armin, Naus Silvia, Vuaroqueaux Vincent, Lamy Evelyn, Fiebig Heiner, Schueler Julia B.. Functional and molecular characteristics of patient-derived xenografts of colon cancer [Abstract]. https://doi.org/10.1158/1535-7163.targ-13-c8
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Lamy Evelyn, Hertrampf Anke, Herz Corinna, Schüler Julia, Erlacher Miriam, Bertele Daniela, Bakare Adekunle, Wagner Meike, Weiland Timo, Lauer Ulrich, Drognitz Oliver, Huber Roman, Rohn Sascha, Giesemann Torsten, Mersch-Sundermann Volker. Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status. https://doi.org/10.1371/journal.pone.0070846
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Lamy Evelyn, Herz Corinna, Lutz-Bonengel Sabine, Hertrampf Anke, Márton Melinda-Rita, Mersch-Sundermann Volker. The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells. https://doi.org/10.1371/journal.pone.0053240
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Lamy Evelyn, Goetz Victoria, Erlacher Miriam, Herz Corinna, Mersch-Sundermann Volker. hTERT: another brick in the wall of cancer cells. https://doi.org/10.1016/j.mrrev.2012.12.005
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2012

Fronza Marcio, Lamy Evelyn, Günther Stefan, Heinzmann Berta, Laufer Stefan, Merfort Irmgard. Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action. https://doi.org/10.1016/j.phytochem.2012.02.015
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Lamy Evelyn, Garcia-Käufer Manuel, Prinzhorn Julia, Mersch-Sundermann Volker. Antigenotoxic action of isothiocyanate-containing mustard as determined by two cancer biomarkers in a human intervention trial. https://doi.org/10.1097/cej.0b013e32834ef140
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Lamy Evelyn, Oey Dewi, Eißmann Florian, Herz Corinna, Münstedt Karsten, Tinneberg Hans‐Rudolf, Mersch‐Sundermann Volker. Erucin and benzyl isothiocyanate suppress growth of late stage primary human ovarian carcinoma cells and telomerase activity in vitro. https://doi.org/10.1002/ptr.4798
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Millet Agnès, Lamy Evelyn, Jonas Daniel, Stintzing Florian, Mersch-Sundermann Volker, Merfort Irmgard. Fermentation enhances the biological activity of allium cepa bulb extracts. https://doi.org/10.1021/jf2041643
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2011

Gründemann Carsten, Papagiannopoulos Menelaos, Lamy Evelyn, Mersch-Sundermann Volker, Huber Roman. Immunomodulatory properties of a lemon-quince preparation (Gencydo®) as an indicator of anti-allergic potency. https://doi.org/10.1016/j.phymed.2010.11.016
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Lamy Evelyn, Schmitz Stefan, Krumbein Angelika, Mersch-Sundermann Volker. Isothiocyanate-containing mustard protects human cells against genotoxins in vitro and in vivo. https://doi.org/10.1016/j.mrgentox.2011.09.004
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Lamy Evelyn, Scholtes Cathy, Herz Corinna, Mersch-Sundermann Volker. Pharmacokinetics and pharmacodynamics of isothiocyanates. https://doi.org/10.3109/03602532.2011.569551
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2010

Fronza M., Günther S., Murillo R., Lamy Evelyn, Heinzmann B., Laufer S., Merfort I.. Cytotoxic abietane diterpenes from Peltodon longipes and their mode of action [Abstract]. https://doi.org/10.1055/s-0030-1264260
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2009

Schmitz Stefan, Prinzhorn Julia, Garcia-Käufer Manuel, Mersch-Sundermann Volker, Lamy Evelyn. A human intervention trial for identification of the chemopreventive properties of isothiocyanates (ITCs) in mustard.
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Wu Xin‐Jiang, Hu Ying, Lamy Evelyn, Mersch‐Sundermann Volker. Apoptosis induction in human lung adenocarcinoma cells by oil‐soluble allyl sulfides: triggers, pathways, and modulators. https://doi.org/10.1002/em.20467
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Lamy Evelyn, Mersch‐Sundermann Volker. MTBITC mediates cell cycle arrest and apoptosis induction in human HepG2 cells despite its rapid degradation kinetics in the in vitro model. https://doi.org/10.1002/em.20448
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Lamy Evelyn, Mersch‐Sundermann Volker. Sulphur‐containing compounds in food plants: Kinetics, biological activity, and mechanisms of action. https://doi.org/10.1002/em.20472
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Lamy Evelyn, Crößmann Catharina, Saeed Adal, Schreiner Peter R., Kotke Mike, Mersch‐Sundermann Volker. Three structurally homologous isothiocyanates exert “Janus” characteristics in human HepG2 cells. https://doi.org/10.1002/em.20470
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2008

Lamy Evelyn, Schröder Julia, Paulus Stefanie, Brenk Peter, Stahl Thorsten, Mersch-Sundermann Volker. Antigenotoxic properties of Eruca sativa (rocket plant), erucin and erysolin in human hepatoma (HepG2) cells towards benzo(a)pyrene and their mode of action. https://doi.org/10.1016/j.fct.2008.03.022
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Lamy Evelyn, Oey Dewi, Eißmann Florian, Mersch-Sundermann Volker. Benzyl isothiocyanate (BITC) and 4-methylthiobutyl isothiocyanate (MTBITC) induce apoptosis in ascites-derived, human ovarian carcinoma cells. https://doi.org/10.1016/j.toxlet.2008.06.664
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Lamy Evelyn, Völkel Yvonne, Roos Peter H., Kassie Fekadu, Mersch-Sundermann Volker. Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion. https://doi.org/10.1016/j.ijheh.2007.04.004
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Stahl Thorsten, Zeuner C.-R., Krawinkel Michael Bernhardt, Lamy Evelyn, Mersch-Sundermann Volker. Identifizierung und Quantifizierung chemopräventiver Isothiocyanate in Brassicaceae.
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Lamy Evelyn, Mersch-Sundermann Volker. Telomerase and its catalytic subunit hTERT are suppressed during the p53-dependent induction of apoptosis mediated by 4-methylthiobutyl isothiocyanate (MTBITC) in human hepatoma cells. https://doi.org/10.1016/j.toxlet.2008.06.665
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2006

Mersch-Sundermann Volker, Bahorun Theeshan, Stahl Thorsten, Neergheen Vidushi S., Soobrattee Muhammad A., Wohlfarth Robert, Sobel Rosa, Brunn Hubertus E., Schmeiser Tim, Lamy Evelyn, Aruoma Okezie I.. Assessment of the DNA damaging potency and chemopreventive effects towards BaP-induced genotoxicity in human derived cells by Monimiastrum globosum, an endemic Mauritian plant. https://doi.org/10.1016/j.tiv.2006.06.014
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Aruoma Okezie I., Colognato Renato, Fontana Ilaria, Gartlon Joanne, Migliore Lucia, Koike Keiko, Coecke Sandra, Lamy Evelyn, Mersch-Sundermann Volker, Laurenza Incoronata, Benzi Luca, Yoshino Fumihiko, Kobayashi Kyo, Lee Masaichi-Chang-Il. Molecular effects of fermented papaya preparation on oxidative damage, MAP Kinase activation and modulation of the benzo[a]pyrene mediated genotoxicity. https://doi.org/10.1002/biof.5520260205
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2004

Lamy Evelyn, Kassie Fekadu, Gminski Richard, Schmeiser Heinz H., Mersch-Sundermann Volker. 3-Nitrobenzanthrone (3-NBA) induced micronucleus formation and DNA damage in human hepatoma (HepG2) cells. https://doi.org/10.1016/j.toxlet.2003.07.001
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